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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083595Generated: October 31, 2026

3-Bromo-5-(trifluoromethyl)pyridine → HCID 178526666, compound

https://huagongshe.com/reaction/1083595

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
ReactantHCID 11173122HCID 11173122—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst1-(Dicyclohexylphosphino)-2-phenyl-1H-indoleHCID 121235231—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178526666HCID 17852666645.66%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-6f65948ef8c64c6e9fc6ea6a07031d42
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide