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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083713Generated: October 28, 2026

Benzonitrile, p-imidazol-1-yl- → HCID 178468654, compound

https://huagongshe.com/reaction/1083713

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, p-imidazol-1-yl-HCID 135744—
ReactantEthyl 4-bromo-1-ethyl-1H-pyrrole-2-carboxylateHCID 78918332—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenylHCID 2734217—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178468654HCID 1784686546.73%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-51ced0a644f342d6ab653013047ee37b
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide