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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083797Generated: November 1, 2026

Benzonitrile, p-imidazol-1-yl- → HCID 178510012, compound

https://huagongshe.com/reaction/1083797

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, p-imidazol-1-yl-HCID 135744—
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst2'-[(1,1-Dimethylethyl)phenylphosphino]-N2,N2,N6,N6-tetramethyl-[1,1'-biphenyl]-2,6-diamineHCID 121237783—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178510012HCID 17851001215.98%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-5effbfa1af4d4df2a70100eca4e34adc
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide