Thionyl Chloride → 1-(Trifluoroacetyl)-2,3-dihydro-1H-indole-5-sulfonyl chloride

HRID 108388Notes

Reaction equation

HRID 108388 reaction equation
[Cl:1][S:2](=[O:3])(=[O:4])[OH:5].[F:6][C:7]([C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21)([F:19])[F:20].[S:21]([Cl:22])([Cl:23])=[O:24]>>[Cl:1][S:2](=[O:3])(=[O:5])[c:15]1[cH:14][c:13]2[c:18]([cH:17][cH:16]1)[N:10]([C:8]([C:7]([F:6])([F:19])[F:20])=[O:9])[CH2:11][CH2:12]2

Participants

4

Reactant 3

HCID 24386Thionyl ChlorideHCID 24638Chlorosulfonic acidHCID 44055422,2,2-Trifluoro-1-indolinylethan-1-one

Product 1

HCID 110883061-(Trifluoroacetyl)-2,3-dihydro-1H-indole-5-sulfonyl chloride

Sources & evidence

ORD record
ord-a6805a22f7f845439e1aa8aa764f4ae3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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