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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083974Generated: November 1, 2026

1-Bromo-2-fluorobenzene → HCID 178456432, compound

https://huagongshe.com/reaction/1083974

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystBrettphosHCID 25112535—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178456432HCID 1784564321.52%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-64dacb4a666d4487b57fef4fbea98435
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide