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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083983Generated: November 1, 2026

1-Bromo-2-fluorobenzene → HCID 178456432, compound

https://huagongshe.com/reaction/1083983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystBis(3,5-bis(trifluoromethyl)phenyl)(3,6-dimethoxy-2',4',6'-tri(propan-2-yl)(1,1'-biphenyl)-2-yl)phosphaneHCID 44597232—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178456432HCID 17845643226.49%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-484c924fc7534c6cab276c544c43e13f
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide