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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083987Generated: November 1, 2026

1-Bromo-2-fluorobenzene → HCID 178456432, compound

https://huagongshe.com/reaction/1083987

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystMethyldiphenylphosphineHCID 73879—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178456432HCID 1784564321.8%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-4a4efb7fba7347698e6376c67b5f63f9
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide