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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1084126Generated: October 30, 2026

1-Methyl-1H-imidazole-4-carbonitrile → HCID 178481279, compound

https://huagongshe.com/reaction/1084126

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-imidazole-4-carbonitrileHCID 2795115—
Reactant5-Bromo-N-tert-butylpyridine-3-sulfonamideHCID 61794951—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst9-[2-(Diethylphosphino)phenyl]-9H-carbazoleHCID 118878622—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178481279HCID 17848127974.35%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-33de2705f45840efaab0395cfcbd002b
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide