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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1084129Generated: October 31, 2026

1-Methyl-1H-imidazole-4-carbonitrile → HCID 178481279, compound

https://huagongshe.com/reaction/1084129

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-imidazole-4-carbonitrileHCID 2795115—
Reactant5-Bromo-N-tert-butylpyridine-3-sulfonamideHCID 61794951—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTris(furan-2-yl)phosphaneHCID 521585—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178481279HCID 17848127966.79%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-5e8b74a1ad424bddadb397173d0dc1c2
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide