HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 14700561, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 8-Chloro-7-fluoro-1-methyl-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine-3-carboxylic acid | HCID 14700554 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14700561 | HCID 14700561 | — |
Reaction Steps
7-Fluoro-1-methyl-8-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-benzo[b][1,8]naphthyridine-3-carboxylic acid is prepared under conditions analogous to Example 1 but starting from 5 g of 8-chloro-7-fluoro-1-methyl-4-oxo-1,4-dihydro-benzo[b][1,8]naphthyridine-3-carboxylic acid and 16 g of 1-methylpiperazine in 50 cm3 of pyridine. After concentrating the reaction mixture
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05004745 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-b1fecaf1cd034b17b116f15f7d786d5e |
| Source note | uspto-grants-1991_04 |