HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 15614800, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 3-Methoxyphenyl isocyanate | HCID 87843 | — |
| Reactant | HCID 15167835 | HCID 15167835 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15614800 | HCID 15614800 | — |
Reaction Steps
Equimolar amounts of 3-(R,S)-amino-1,3-dihydro-1,8-dimethyl-5-phenyl-2H-1,4-benzodiazepin-2-one, 3-methoxyphenylisocyanate, and triethylamine were mixed in THF at 0° C. and stirred 20 minutes. Removal of THF in vacuo and crystallization from MeOH gave the title compound: m.p. 184°-188° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05004741 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-feacff38d8fa4f1dbc2993d9c658c1f4 |
| Source note | uspto-grants-1991_04 |