Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Phthalide | HCID 6885 | — |
| Reactant | (4-Nitrophenyl)hydrazine | HCID 3310889 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 15702298 | HCID 15702298 | 10.2% |
Reaction Steps
To prepare compound I-24 identified above, 38.3 g of p-nitrophenylhydrazine and 33 g of phthalide were heated in acetonitrile for 3 hours at 70°-80° C. After cooling to 20° C., the solid product was stirred together with ether and then the product was collected by filtration and washed with ether to obtain 7.2 g of 1-(2'-hydroxymethylbenzoyl)-2-(p-nitrophenyl)hydrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05006445 |
|---|
| Source dataset | uspto-grants-1991_04 |
|---|
| ORD ID | ord-9594c7f17f8747cdabcc1fffec3c8341 |
|---|
| Source note | uspto-grants-1991_04 |
|---|
