HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 178517243, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | 5,11-dihydro-11-(2-propynyl)-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 14552085 | — |
| Reactant | HCID 178511287 | HCID 178511287 | — |
| Product | HCID 178517243 | HCID 178517243 | 31% |
Reaction Steps
Prepared analogously to Example lb) from 5,11-dihydro-11-(prop-2-ynyl)-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, paraformaldehyde and trans-(4-hydroxy-cyclohexyl)methylamine in a yield of 31% of theory. Colourless crystals, m.p. 183°-184° C. (after recrystallisation from ethyl acetate and methanol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006522 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-2a05f5f7ab2148d9a9da5a4b88e15c91 |
| Source note | uspto-grants-1991_04 |