HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl isocyanate → Methyl 3-benzyl-2-isoxazolin-5-yl(P-methyl)phosphinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl isocyanate | HCID 7672 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Nitro-2-phenylethane | HCID 80208 | — |
| Reactant | Methyl methylvinylphosphinate | HCID 6454580 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Methyl 3-benzyl-2-isoxazolin-5-yl(P-methyl)phosphinate | HCID 20062386 | 79% |
Reaction Steps
Preparation is carried out in analogy to Example 23 from 37.1 ml (0.34 mol) of phenyl isocyanate, 22.5 g (0.187 mol) of methyl vinyl(P-methyl)phosphinate, 4 ml of triethylamine and 25.7 g (0.17 mol) of 2-phenylnitroethane in toluene, resulting in 34 g of brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006515 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-a078aed30ebf450481812bf743e1fd6f |
| Source note | uspto-grants-1991_04 |