Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Chloride → Methyl 3-tert.butyl-2-isoxazolin-5-yl(P-methyl)phosphinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Chloride | HCID 312 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Chlorosuccinimide | HCID 31398 | — |
| 반응물 | Pivalaldoxime | HCID 136457 | — |
| 반응물 | Methyl methylvinylphosphinate | HCID 6454580 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Methyl 3-tert.butyl-2-isoxazolin-5-yl(P-methyl)phosphinate | HCID 20062412 | 50% |
반응 단계
40.4 g (0.4 mol) of pivalaldoxime are converted in analogy to Example 1(a) with 58.7 g (0.44 mol) of N-chlorosuccinimide and 2 ml of pyridine in dichloromethane into the hydroxamoyl chloride which is subsequently reacted with 52.8 g (0.44 mol) of methyl vinyl(P-methyl)phosphinate and 61.2 ml (0.44 mol) of triethylamine, and worked up, as described in Example 1(b), the oily product being obtained with a yield of about 50%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05006515 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-a497d412dcde41f0bf2239586dc15ebe |
| 출처 메모 | uspto-grants-1991_04 |