Ethyl bromoacetate → HCID 14796395, compound

Participants

Reaction Steps

4-(1-Phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl)phenoxyacetic acid can be produced by reacting 3-(4-hydroxyphenyl)-1-phenyl1H-pyrazolo[3,4-b]pyridine with ethyl bromoacetate in the presence of potassium carbonate as a deacidifying agent in dimethylformamide to obtain ethyl 4-(1-phenyl-1H-pyrazolo[3,4-b]pyridin-3-yl)phenoxyacetate, followed by hydrolysis thereof with the use of sodium hydroxide.

Provenance & Evidence