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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1084838Generated: October 25, 2026

Morpholine, 4-(chloroacetyl)- → 4-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}morpholine

https://huagongshe.com/reaction/1084838

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholine, 4-(chloroacetyl)-HCID 74040—
Reactant3-(4-fluorophenyl)-1-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridineHCID 14796258—
Product4-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}morpholineHCID 15158071—

Reaction Steps

By conducting reactions and treatments in the same manner as in Examples 1-6, using 3-(4-fluorophenyl)-1-(3-hydroxyphenyl)-1H-pyrazolo[3,4-b]pyridine and 4-chloroacetylmorpholine, there was obtained 4-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}morpholine, m.p. 141°-143° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05006520
Source datasetuspto-grants-1991_04
ORD IDord-99e78a7d513f4b3892ffd59e60f0dec8
Source noteuspto-grants-1991_04