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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1084841Generated: October 25, 2026

1-Methylpiperazine → 1-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}-4-methylpiperazine

https://huagongshe.com/reaction/1084841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetic acidHCID 14796398—
Product1-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}-4-methylpiperazineHCID 14796331—

Reaction Steps

By conducting reactions and treatments in the same manner as in Examples 36 and 37, using 3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetic acid and 4-methylpiperazine, there was obtained 1-{3-[3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-1-yl]phenoxyacetyl}-4-methylpiperazine, m.p. 132°-135° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05006520
Source datasetuspto-grants-1991_04
ORD IDord-ca0657e4f1e448a493b163172d6d2d6c
Source noteuspto-grants-1991_04