Sodium Hydroxide → HCID 85882735, compound

HRID 1084897Notes

Reaction equation

HRID 1084897 reaction equation
Cl.[C:2]([NH:6][NH2:7])([CH3:5])([CH3:4])[CH3:3].[OH-].[Na+].[C:10]1([CH2:16][CH2:17][C:18](=O)[CH3:19])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>O>[C:2]([NH:6][N:7]=[C:18]([CH2:17][CH2:16][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH3:19])([CH3:5])([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 17355Benzyl acetoneHCID 81889tert-Butylhydrazine monohydrochloride

Product 1

HCID 85882735HCID 85882735, compoundYield 49%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 50.46 g t-butyl hydrazine hydrochloride and 32 g of 50 percent aqueous sodium hydroxide in 70 ml of water is stirred in an ice water bath. About 55 g of 4-phenyl-2-butanone is added with stirring. The reaction and isolation are continued as in Example (a). The title compound is isolated as a fraction distilled under 0.9 mm pressure at 110° C.-119° C. The yield is about 49 percent based upon the initial amount of 4-phenyl-2-butanone added.

Workup

  1. customThe reaction and isolation

Sources & evidence

ORD record
ord-2c67581152074631a4cebd7bb68ef62d
Source dataset
uspto-grants-1991_04
Patent number
US05006567

Reaction notes

Loading…