Ammonia → HCID 13983523, compound

HRID 1084933Notes

Reaction equation

HRID 1084933 reaction equation
Br[C:2]1[C:11]([S:12]([CH2:15][CH3:16])(=[O:14])=[O:13])=[CH:10][C:9]([C:17]([OH:19])=[O:18])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][O:7]2.[NH3:20]>[Cu]>[NH2:20][C:2]1[C:11]([S:12]([CH2:15][CH3:16])(=[O:14])=[O:13])=[CH:10][C:9]([C:17]([OH:19])=[O:18])=[C:8]2[C:3]=1[CH2:4][CH2:5][CH2:6][O:7]2

Participants

4

Reactant 2

HCID 222AmmoniaHCID 13983522HCID 13983522, compound

Product 1

HCID 13983523HCID 13983523, compound

Reagents, catalysts & solvents 1

HCID 23978CopperCatalyst

Procedure

118 g of 5-bromo-6-ethylsulphonylchroman-8-carboxylic acid, 460 ml of 34% ammonia, 5 g of powdered copper and 4 g of cuprous chloride were introduced into a 1-liter autoclave and the contents were then heated between 115° and 120° C., for 10 to 12 hours, with stirring.

Workup

  1. temperaturethe contents were then heated between 115° and 120° C., for 10 to 12 hours

Sources & evidence

ORD record
ord-5823db2771ae4723882f0fd63ab153e1
Source dataset
uspto-grants-1991_04
Patent number
US05006570

Reaction notes

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