HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 15472615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 4-Phenyl-3-Buten-2-one | HCID 15909 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Catalyst | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Product | HCID 15472615 | HCID 15472615 | — |
Reaction Steps
The organo magnesium compound is then added to a solution of 10 g (0.068 mole) of benzalacetone and 7% (0.97 g) of CuI in 250 ml of THF. The mixture rapidly assumes a brown colouring. After addition, it is left for a few minutes at reflux and then 12 hours at ambient temperature. Hydrolyzing takes place by the addition of the reaction mixture to crushed ice and ammonium chloride, accompanied by very vigorous stirring. After 2 hours, the mixture assumes a blue lavender shade. Extraction takes place with ether and the product is dried on sodium sulphate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006663 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-4ba6911dbe794f94b9595193caa67e8c |
| Source note | uspto-grants-1991_04 |