反应详情

2.3 ml of a 28% solution of sodium methoxide in methanol and 63 mg of copper powder were added to 40 ml of methanol, and the mixture was heated under reflux for 1 hour. Then, 145 mg of 8-hydroxyquinoline and 2.14 g of 2-bromo-1-acetylaminobenzene were added thereto, and the mixture was heated under reflux for 3 hours. The reaction mixture was treated in a usual manner, to obtain 1.43 g (yield: 87%) of the desired compound.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 1 hour
3. temperaturethe mixture was heated
4. temperatureunder reflux for 3 hours
5. additionThe reaction mixture was treated in a usual manner