HRID1085001

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21631

1,3-Isobenzofurandione, 4-nitro-

C8H3NO5

结构：CC(=O)O.CNC(=O)[C@H](CC(C)C)NC(=O)C(CC(C)C)CP(=O)(CN)OC

HCID86743557

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)C(CC(C)C)NC(=O)C(CC(C)C)CP(=O)(CN1C(=O)c2cccc([N+](=O)[O-])c2C1=O)OC

HCID54472480

未命名化合物

收率 35.9%

PROCEDURE

实验过程

In a manner analogous to that described in Example 3(A), from 0.23 g of (aminomethyl)[(RS)-4-methyl-2-[[(S)-3-methyl-1-(methylcarbamoyl)butyl]carbamoyl]pentyl]phosphinic acid methyl ester acetate and 0.105 g of 3-nitrophthalic anhydride, there was obtained 0.105 g of [4-methyl-2-[[3-methyl-1-(methylcarbamoyl)butyl]carbamoyl]pentyl][(3-nitrophthalimido)methyl]phosphinic acid methyl ester in the form of a pale yellow foam.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c30e10b8ffec48cc8ed8e74e8c8873e0
来源数据集: uspto-grants-1991_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05006651
来源说明: uspto-grants-1991_04

反应 SMILES

C(O)(=O)C.[CH3:5][O:6][P:7]([CH2:27][NH2:28])([CH2:9][CH:10]([C:15](=[O:26])[NH:16][C@H:17]([C:22](=[O:25])[NH:23][CH3:24])[CH2:18][CH:19]([CH3:21])[CH3:20])[CH2:11][CH:12]([CH3:14])[CH3:13])=[O:8].[N+:29]([C:32]1[CH:42]=[CH:41][CH:40]=[C:34]2[C:35]([O:37][C:38](=O)[C:33]=12)=[O:36])([O-:31])=[O:30]>>[CH3:5][O:6][P:7]([CH2:9][CH:10]([C:15](=[O:26])[NH:16][CH:17]([C:22](=[O:25])[NH:23][CH3:24])[CH2:18][CH:19]([CH3:21])[CH3:20])[CH2:11][CH:12]([CH3:14])[CH3:13])([CH2:27][N:28]1[C:38](=[O:37])[C:33]2=[C:32]([N+:29]([O-:31])=[O:30])[CH:42]=[CH:41][CH:40]=[C:34]2[C:35]1=[O:36])=[O:8]