HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvalerate → 2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvalerate | HCID 86743562 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[[(Ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid | HCID 20063016 | — |
Reaction Steps
4.5 g of benzyl (R or S)-2-[[(ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvalerate were dissolved in 120 ml of ethanol and the solution was hydrogenated over 1.6 g of 10% palladium-on-charcoal for 5.5 hours. After filtration and evaporation of the filtrate, there were obtained 3.0 g of (R or S)-2-[[(ethoxy)(phthalimidomethyl)phosphinyl]methyl]-4-methylvaleric acid in the form of a white foam.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05006651 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-b8c93bd84f20418cb0e639289bf6cf6e |
| Source note | uspto-grants-1991_04 |