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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085059Generated: November 1, 2026

4-(2-Chloroethyl)morpholine → 2-(2-Morpholinoethylthio)-3-phenyl-4(3H)-quinazolinone

https://huagongshe.com/reaction/1085059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Chloroethyl)morpholineHCID 76727—
ReactantHCID 178515047HCID 178515047—
Product2-(2-Morpholinoethylthio)-3-phenyl-4(3H)-quinazolinoneHCID 1457515549.8%

Reaction Steps

The title compound was prepared in a yield of 49.8%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3- isobutyl-2-mercapto-4(3H)-quinazolinone and N-(2-chloroethyl)morpholine in place of 2-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05008266
Source datasetuspto-grants-1991_04
ORD IDord-884820ec401645e587cb35861afbaddf
Source noteuspto-grants-1991_04