2-(chloromethyl)-N,N-dimethylaniline → HCID 14575158, compound

HRID 1085061Notes

Reaction equation

HRID 1085061 reaction equation
[SH:1][C:2]1[N:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:10](=[O:18])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.Cl[CH2:20][C:21]1[CH:29]=[CH:28][CH:27]=[CH:26][C:22]=1[N:23]([CH3:25])[CH3:24]>>[CH3:24][N:23]([CH3:25])[C:22]1[CH:26]=[CH:27][CH:28]=[CH:29][C:21]=1[CH2:20][S:1][C:2]1[N:11]([C:12]2[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=2)[C:10](=[O:18])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 107734552-(chloromethyl)-N,N-dimethylanilineHCID 178515047HCID 178515047, compound

Product 1

HCID 14575158HCID 14575158, compoundYield 26.9%

Procedure

The title compound was prepared in a yield of 26.9%, using 2-mercapto-3-phenyl-4(3H)-quinazolinone in place of 3- isobutyl-2-mercapto-4(3H)-quinazolinone and 2-chloromethyl-N,N-dimethylaniline in place of 2-choromethylpyridine hydrochloride.

Sources & evidence

ORD record
ord-ad6d8d8a8f9843f2ae4688685aa77a65
Source dataset
uspto-grants-1991_04
Patent number
US05008266

Reaction notes

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