反应详情

温度

110 °C

4-cyclopropylmethoxy-2-methylpyridine-1-oxide (3.8 g 0.021 mol) was dissolved in acetic anhydride (10 ml) and was added dropwise to acetic anhydride (20 ml) (warmed to 90° C.). After the addition the temperature was raised to 110° C. and the mixture was stirred at 110° C. for 1 h and then the solvent was distilled off and the crude product was used without purification. NMR data is given below.

1. additionAfter the addition the temperature
2. distillationthe solvent was distilled off
3. customthe crude product was used without purification