Ethanesulfonyl chloride → HCID 20061013, compound

Participants

Reaction Steps

A suspension of the aniline from example 14 (0.5 g, 1.3 mmol) in dry pyridine (3 ml) was treated with ethanesulphonyl chloride (0.133 ml, 1.4 mmol). After 1 h, the mixture was evaporated to dryness then partitioned between dichloromethane and dilute aqueous sodium bicarbonate. The organic phase was dried over magnesium sulphate and evaporated to a yellow solid which was recrystallised from ethyl acetate (0.37 g, 59%). M.p. 258°-260° C.

Provenance & Evidence