3-Methyl-1-(pyridin-2-yl)-1H-pyrazol-5-amine → HCID 5138169, compound

Participants

Reaction Steps

By the method of Preparation 8(a), 5-amino-3-methyl-1-(2-pyridyl)pyrazole (2.21 g, 12.7 mmol) was treated with sodium nitrite in aqueous acetic acid. The precipitated solid was triturated with methanol (250 ml), and the mother liquors were concentrated under reduced pressure to give the title compound as a red-brown solid (1.37 g, 53%).

Provenance & Evidence