HCID 5138169, compound → HCID 20061021, compound

HRID 1085157Notes

Reaction equation

HRID 1085157 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)[N:5]=[C:4]([CH3:13])[C:3]=1[N:14]=O>C(O)C.ClCCl.[Pd]>[NH2:14][C:3]1[C:4]([CH3:13])=[N:5][N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][N:8]=2)[C:2]=1[NH2:1]

Participants

4

Reactant 1

HCID 5138169HCID 5138169, compound

Product 1

HCID 20061021HCID 20061021, compoundYield 100%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 21584144Dichloromethane ethanolSolvent

Procedure

By the method of Preparation 8(b), 5-amino-3-methyl-4-nitroso-1-(2-pyridyl)pyrazole (1.37 g, 6.75 mmol) in ethanol/dichloromethane=4:1 (50 ml) was hydrogenated over 10% palladium on carbon at 20 p.s.i. to give the title compound (1.27 g, 100%).

Sources & evidence

ORD record
ord-970478b7d6044ed6b58ad8387d0e91e3
Source dataset
uspto-grants-1991_04
Patent number
US05008263

Reaction notes

Loading…