Ethyl γ-methyl-4-nitrobenzenebutanoate → HCID 12561714, compound

Participants

Reaction Steps

A mixture of 114 g of ethyl 4-(4-nitrophenyl)pentanoate, 170 ml of absolute ethanol and 2 g of 10% of palladium-on-charcoal was hydrogenated on a Paar shaker until consumption of hydrogen ceased. The catalyst was collected and the ethanol evaporated. The residue was partitioned between water and ether. The ether extract was washed with 5% of sodium bicarbonate solution and water, dried over anhydrous sodium sulfate, filtered and evaporated to give 85 g (86%) of product, bp 118°-122° C. (0.55-0.60 mm).

Provenance & Evidence