HCID 10069734, compound → HCID 20061364, compound

HRID 1085253Notes

Reaction equation

[CH3:1][N:2]1[C:7]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=3)[CH2:10][CH2:9]2)=[CH:6][C:5](=[O:27])[N:4]([CH3:28])[C:3]1=[O:29].[ClH:30].CO>>[ClH:30].[CH3:1][N:2]1[C:7]([N:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][O:17][C:18]3[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=3)[CH2:10][CH2:9]2)=[CH:6][C:5](=[O:27])[N:4]([CH3:28])[C:3]1=[O:29]

Participants

Reactant 2

HCID 10069734HCID 10069734, compound

HCID 21893726Hydrochloride methanol

Product 1

HCID 20061364HCID 20061364, compound

Procedure

Furthermore, the thus obtained 1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione was treated with a hydrochloric acid/methanol solution in a usual manner to obtain 1,3-dimethyl-6-{4-[3-(4-nitrophenoxy)propyl]piperazin-1-yl}-2,4(1H,3H)-pyrimidinedione hydrochloride (compound 35).

Sources & evidence

ORD record: ord-25cb7accfe7e4d2b873f24e05316be95
Source dataset: uspto-grants-1991_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05008267

Reaction notes

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