4-Chlorobenzoyl chloride → 6-(4-Chlorobenzoyl)-(6H)-dibenz[c,e][1,2]oxaphosphorin 6-oxide

HRID 1085371Notes

Reaction equation

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.C[O:12][P:13]1[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=2[C:16]2[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=2[O:14]1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([P:13]2(=[O:12])[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][C:17]=3[C:16]3[CH:23]=[CH:24][CH:25]=[CH:26][C:15]=3[O:14]2)=[O:7])=[CH:4][CH:3]=1

Participants

Conditions

Temperature: 130 °C

Procedure

35 g (0.2 mol) of 4-chlorobenzoyl chloride were warmed to 90° to 100° C. under a nitrogen atmosphere. 46 g of 6-methoxy-(6H)-dibenz[c,e][1,2]oxaphosphorin were added dropwise while stirring. The internal temperature was then increased gradually to 130° C. When the reaction was complete, the mixture was digested with 50 ml of toluene. 60 g (85% of theory) of the abovementioned substance of melting point 125° to 131° C. were obtained.

Workup

custom60 g (85% of theory) of the abovementioned substance of melting point 125° to 131° C. were obtained

Sources & evidence

ORD record: ord-e711d8c4a1bd4f72b102e0f4a30a66d4
Source dataset: uspto-grants-1991_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05008426

Reaction notes

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