Water → HCID 53812675, compound

Participants

Reaction Steps

At 5° to 10° C., 10.4 g (0.04 mol) of 2-chloro-5-nitro-α-methylcinnamyl chloride in 100 ml of tetrahydrofuran was added to 4.6 g (0.08 mol) of alkylamine in 50 ml of tetrahydrofuran. After 2 hours the solvent was stripped off, and the remaining mixture was stirred into water. The solid which formed was isolated. Drying of the solid gave 8.1 g (81% of theory) of 2-chloro-5-nitro-α-methylcinnamic acid-N-allylamide of m.p. 111°-112° C.

Provenance & Evidence