HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1085402Generated: October 25, 2026
3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl)-1,3-dihydro-2(2H)-indolone → 3-(Ethylthio)-5-fluoro-3-{2-[4-(7-methoxy-1,2,3,4-tetrahydro-1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone
https://huagongshe.com/reaction/1085402
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl)-1,3-dihydro-2(2H)-indolone | HCID 14601167 | — |
| Reactant | (7-Methoxytetralin-1-yl)piperazine | HCID 14601169 | — |
| Product | 3-(Ethylthio)-5-fluoro-3-{2-[4-(7-methoxy-1,2,3,4-tetrahydro-1-naphthyl)-1-piperazinyl]ethyl}-1,3-dihydro-2(2H)-indolone | HCID 14601170 | — |
Reaction Steps
A mixture of 8.1 g (0.0328 mole) of 1-(7-methoxy-1,2,3,4-tetrahydro-1-naphthyl)piperazine and 6.7 g (0.0164 mole) of 3-(ethylthio)-5-fluoro-3-(2-hydroxyethyl)-1,3-dihydro-2(2H)-indolone is heated to 110° C. for 1 hour.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05010079 |
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| Source dataset | uspto-grants-1991_04 |
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| ORD ID | ord-0ea5c0200e5440eab6e321bc11418ee2 |
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| Source note | uspto-grants-1991_04 |
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