4-Fluoroaniline → HCID 14601197, compound

HRID 1085404Notes

Reaction equation

[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][CH:3]=1.ClOC(C)(C)C.[CH2:15]([S:17][CH:18]([CH3:24])[C:19](OCC)=[O:20])[CH3:16]>>[CH2:15]([S:17][C:18]1([CH3:24])[C:7]2[C:5](=[CH:4][CH:3]=[C:2]([F:1])[CH:8]=2)[NH:6][C:19]1=[O:20])[CH3:16]

Participants

Reactant 3

HCID 97314-Fluoroaniline

HCID 521297Tert-Butyl hypochlorite

HCID 554558Propanoic acid, 2-(ethylthio)-, ethyl ester

Product 1

HCID 14601197HCID 14601197, compound

Procedure

The compound is prepared as described under 1.1, starting with 24.4 g (0.22 mole) of 4-fluoroaniline, 26.2 ml of t-butyl hypochlorite and 35.7 g (0.22 mole) of ethyl 2(ethylthio)propanoate.

Workup

customThe compound is prepared

Sources & evidence

ORD record: ord-17fc9a46ef6c4600b12fd8392d78a794
Source dataset: uspto-grants-1991_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05010079

Reaction notes

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