HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethylamine → N-(2-Phenylethyl)-9H-pyrido[3,4-b]indole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethylamine | HCID 1001 | — |
| Reactant | Ethyl Beta-Carboline-3-Carboxylate | HCID 105078 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(2-Phenylethyl)-9H-pyrido[3,4-b]indole-3-carboxamide | HCID 1778329 | 95.2% |
Reaction Steps
2 g of ethyl β-carbolin-3-carboxylate and 5 g of β-phenethylamine are heated for 2 hours at 196° C. The cooled, partly crystallized mixture is treated with hot water which is decanted. The residue is recrystallized from xylene to form β-carbolin-3-carboxylic acid (2-phenylethyl)amide (2.5 g) of a melting point of 297°-298° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05010077 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-df915842a0f94e0ab34b33c824664bb8 |
| Source note | uspto-grants-1991_04 |