HCID 18633382, compound → HCID 53989383, compound

Participants

Reaction Steps

A solution of 0.2 g of 2',5'-dideoxy-5-ethyl-5'-[2-(2nitrophenyl)acetamido]uridine in 100 ml of ethanol was hydrogenated over 0.1 g of 10% palladium-on-carbon catalyst at room temperature and under atmospheric pressure until the uptake of hydrogen was complete. The mixture was filtered and the filtrate was evaporated to yield an oil which crystallized from ethanol to give 0.1 g of 5'-[2-(2-aminophenyl)acetamido]2',5'-dideoxy-5-ethyluridine in the form of a white solid of melting point 195°-196° C.

Provenance & Evidence