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HRID1085538

反应详情

EQUATION

反应方程式

HRID 1085538 的结构方程式

REACTANTS

反应物

1
结构：CCc1cn([C@H]2C[C@H](O)[C@@H](CN(C)Cc3ccccc3)O2)c(=O)[nH]c1=O
HCID54104497

未命名化合物

PRODUCTS

生成物

1
结构：CCc1cn([C@H]2C[C@H](O)[C@@H](CNC)O2)c(=O)[nH]c1=O
HCID18633445

未命名化合物

收率 101.9%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Pd]
催化剂HCID23938

Palladium

Pd

结构：CCO
溶剂HCID702

Ethanol

C2H6O

2 次

PROCEDURE

实验过程

1.1 g of 2',5'-dideoxy-5-ethyl-5'-(N-methyl-N-benzylamino)uridine were taken up in 75 ml of ethanol and 1 g of palladium-on-carbon catalyst in 25 g ml of ethanol was added under a nitrogen atmosphere. The mixture was hydrogenated at room temperature and under atmospheric pressure. The catalyst was removed by filtration and the filtrate was evaporated to give 0.84 g of 2',5'-dideoxy-5-ethyl-5'methylaminouridine of melting point 145°-147° C.

WORKUP

后处理

  1. customwas hydrogenated at room temperature and under atmospheric pressure
  2. customThe catalyst was removed by filtration
  3. customthe filtrate was evaporated