Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4,5-Dichloro-2-(3,4-dichlorophenyl)-1-(ethoxymethyl)pyrrole-3-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Chloromethyl ethyl ether | HCID 18523 | — |
| 반응물 | 4,5-dichloro-2-(3,4-dichlorophenyl)-1H-pyrrole-3-carbonitrile | HCID 183555 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4,5-Dichloro-2-(3,4-dichlorophenyl)-1-(ethoxymethyl)pyrrole-3-carbonitrile | HCID 15010140 | — |
반응 단계
A sample of 4,5-dichloro-2-(3,4-dichlorophenyl)pyrrole-3-carbonitrile (1.0 g, 0.003 mole) is dissolved in 10 mL of dry tetrahydrofuran. To this solution is added potassium t-butoxide (0.37 g, 0.0033 mole) followed by chloromethyl ethyl ether (0.312 g, 0.0033 mole) The mixture is stirred for about 1 hour at room temperature and then poured into a large volume of water precipitating the product. The white solid is collected and dried to give 1.0 g (91%) with m.p. 128°-130°.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05010098 |
| 출처 데이터셋 | uspto-grants-1991_04 |
| ORD ID | ord-27dc1d58a14842b0af66cb8b5a79a204 |
| 출처 메모 | uspto-grants-1991_04 |