HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → N-isopropylhexahydropyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | N-Isopropylpropane-1,3-diamine | HCID 76888 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | N-isopropylhexahydropyrimidine | HCID 12676275 | 78% |
Reaction Steps
A solution of N-isopropyl-1,3-propanediamine (116 g, 1 M) in isopropyl alcohol (1 l ) maintained ca 10° was treated dropwise with 40% aqueous HCHO solution (75 ml, 1 M). After 1 hour the solvents were evaporated under reduced pressure and the residue distilled to give N-isopropylhexahydropyrimidine (100 g, 78%), Bp 65° /20 mbar.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05010196 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-4c6f9245f5474f7d8e739c2cd5244c84 |
| Source note | uspto-grants-1991_04 |