HCID 14261125, compound → HCID 11151551, compound

Participants

Reaction Steps

21.3 g (0.06 mol) of 5(S)-azido-6-cyclohexyl-4(S)-hydroxy-2(S)-isopropylhexanoic acid n-butylamide in 240 ml of methanol are hydrogenated for 2 hours in the presence of 5 g of 10% palladium-on-carbon. The reaction mixture is filtered, concentrated in a rotary evaporator, and the residue is recrystallised from hexane: m.p. 88.5°-90°; [α]D -27.2°±0.9° (c=1.1, CHCl3).

Provenance & Evidence