Thionyl Chloride → HCID 14718889, compound

HRID 1085717Notes

Reaction equation

HRID 1085717 reaction equation
[CH3:1][O:2][CH2:3][C:4]1[C:12]([F:13])=[C:11]([F:14])[C:7]([C:8](O)=[O:9])=[C:6]([F:15])[C:5]=1[F:16].S(Cl)([Cl:19])=O>>[CH3:1][O:2][CH2:3][C:4]1[C:12]([F:13])=[C:11]([F:14])[C:7]([C:8]([Cl:19])=[O:9])=[C:6]([F:15])[C:5]=1[F:16]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 139114712,3,5,6-Tetrafluoro-4-(methoxymethyl)benzoic acid

Product 1

HCID 14718889HCID 14718889, compound

Procedure

4-(Methoxymethyl)-2,3,5,6-tetrafluorobenzoic acid [5.0 g prepared by a process similar to that described in European Patent Application No 54360] was dissolved in thionyl chloride (50 cm3) and heated to the reflux temperature with stirring for 3 hours. The excess thionyl chloride was evaporated under reduced pressure to yield 4-(methoxymethyl)-2,3,5,6-tetrafluorobenzoyl chloride (ca 5 g) as a pale yellow liquid.

Workup

  1. temperatureheated to the reflux temperature
  2. customThe excess thionyl chloride was evaporated under reduced pressure

Sources & evidence

ORD record
ord-ef815e4e5a0c4c598f6d0c24f1716b43
Source dataset
uspto-grants-1991_04
Patent number
US05010200

Reaction notes

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