Benzocaine → HCID 15734501, compound

HRID 1085763Notes

Reaction equation

HRID 1085763 reaction equation
[NH2:1][C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.Cl[C:14](Cl)(Cl)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[Cl:21]>C(Cl)(Cl)Cl>[CH2:9]([O:8][C:6]([C:5]1[CH:4]=[CH:3][C:2]([NH:1][C:14](=[N:1][C:2]2[CH:3]=[CH:4][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:11][CH:12]=2)[C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[Cl:21])=[CH:12][CH:11]=1)=[O:7])[CH3:10]

Participants

4

Reactant 2

HCID 2337BenzocaineHCID 16494Benzene, 1-chloro-2-(trichloromethyl)-

Product 1

HCID 15734501HCID 15734501, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

N,N'-Bis(4-ethoxycarbonylphenyl)-2-chlorobenzamidine (10) was prepared from ethyl 4-aminobenzoate and α,α,α,2-tetrachlorotoluene; tan solid: mp 98°-108° C. 1H-NMR (CDCl3) 8.3-6.4 (m, 13H), 4.2 (q, 4H, J=7 Hz); IR (CHCl3) 3360, 1695, 1600, 1580; MS (m/e) 450, 452 (M+), 286 (base).

Sources & evidence

ORD record
ord-3f4f0e3c6e954d0ba9960c2e6d5a051c
Source dataset
uspto-grants-1991_04
Patent number
US05011628

Reaction notes

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