Benzyl Bromide → HCID 77374747, compound

Participants

Reaction Steps

A solution of 6.9 g of the alcohol 3, 1.68 g of sodium hydride, 300 mg of tetrabutylammonium iodide and 5.95 g of benzyl bromide in 250 ml of THF was stirred for 4 hours at 60° C. At the end of this time 100 ml of saturated aqueous ammonium chloride solution was added and the mixture extracted with 200 ml of EtOAc and the organic phase was dried with sodium sulfate. Concentration under vacuum provided the title compound.

Provenance & Evidence