Ethanol → Benzoic acid [1-(4-pyridinyl)ethylidene]hydrazide 1-oxide

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Reaction Steps

A mixture of 5.48 gm (0.04 mole) of 4-acetylpyridine 1-oxide, 5.45 gm (0.04 mole) of benzhydrazide and 100 ml of absolute ethanol is refluxed for a total of 4 hr and cooled. The reaction mixture is evaporated in vacuo to yield a solid which is crystallized from ethanol to yield 7.82 gm (77%) of the title compound having a melting point of 248.9° C. (decomp).

Provenance & Evidence