Oxalic Acid → HCID 86152381, compound

HRID 1085961Notes

Reaction equation

HRID 1085961 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1.[C:16]([OH:21])(=[O:20])[C:17]([OH:19])=[O:18]>C(O)C>[C:16]([OH:21])(=[O:20])[C:17]([OH:19])=[O:18].[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 53879071HCID 53879071, compound2×

Product 1

HCID 86152381HCID 86152381, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 6.15 gm (0.03 mole) of butyric acid [1-(4-pyridinyl)ethylidene]hydrazide (Compound 144), 2.70 gm (0.03 mole) of oxalic acid and 100 ml of absolute ethanol is refluxed 3 hr. The mixture is cooled and then chilled in the refrigerator. Two crops of the product are collected and dried to yield 6.9 gm (78%) of the title compound having a melting point of 207.2° C.

Workup

  1. temperatureis refluxed 3 hr
  2. temperatureThe mixture is cooled
  3. temperaturechilled in the refrigerator
  4. customTwo crops of the product are collected
  5. customdried

Sources & evidence

ORD record
ord-77233bc57e6c46c8b67a92844c12fddb
Source dataset
uspto-grants-1991_04
Patent number
US05011932

Reaction notes

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