Phenoxyacetic Acid → HCID 86744749, compound

HRID 1085963Notes

Reaction equation

HRID 1085963 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1.[O:16]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(O)C>[O:16]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[N:9][NH:10][C:11](=[O:15])[CH2:12][CH2:13][CH3:14])[CH3:8])=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 19188Phenoxyacetic AcidHCID 53879071HCID 53879071, compound2×

Product 1

HCID 86744749HCID 86744749, compoundYield 66.3%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 8.2 gm (0.04 mole) of butyric acid [1-(4-pyridinyl)ethylidene]hydrazide (Compound 144), 6.09 gm (0.04 mole) of phenoxyacetic acid and 100 ml of absolute ethanol is refluxed 7.5 hr. The reaction mixture is evaporated to dryness in vacuo. The solid is crystallized from ethanol to yield 9.48 gm (66%) of the title compound having a melting point of 105.8° C.

Workup

  1. temperatureis refluxed 7.5 hr
  2. customThe reaction mixture is evaporated to dryness in vacuo
  3. customThe solid is crystallized from ethanol

Sources & evidence

ORD record
ord-7573798c540744deaa12c5f3c56e6086
Source dataset
uspto-grants-1991_04
Patent number
US05011932

Reaction notes

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