反应详情

A mixture of 5.48 gm (0.04 mole) of 4-acetylpyridine 1-oxide, 4.09 gm (0.04 mole) of butyric acid hydrazide and 100 ml of absolute ethanol is refluxed 6 hours. The reactions mixture is evaporated in vacuo to give a solid. The crude product is crystallized from ethyl acetate/ethanol to yield 7.41 gm (84%) of the title compound; mp 209.7°.

1. temperatureis refluxed 6 hours
2. customThe reactions mixture is evaporated in vacuo
3. customto give a solid
4. customThe crude product is crystallized from ethyl acetate/ethanol