HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Acetylpyridine → Cyclobutanecarboxylic acid [1-(4-pyridinyl)ethylidene]hydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Acetylpyridine | HCID 14282 | — |
| Reactant | Cyclobutanecarbohydrazide | HCID 969366 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Cyclobutanecarboxylic acid [1-(4-pyridinyl)ethylidene]hydrazide | HCID 54267191 | 27% |
Reaction Steps
A mixture of 6.06 gm (0.05 mole) of 4-acetylpyridine, 5.7 gm (0.05 mole) of cyclobutanecarboxylic acid hydrazide, and 100 ml of absolute ethanol is refluxed 5 hours. The reaction mixture is evaporated in vacuo to give a solid. The product is crystallized from ethanol/ethylacetate/diethylether to give 2.92 gm (27%) of the title compound; mp 138.6°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05011932 |
| Source dataset | uspto-grants-1991_04 |
| ORD ID | ord-4633c2f138e6438580d225cf4a6e4313 |
| Source note | uspto-grants-1991_04 |